Headaches

17th December, 2008 - Posted by Andy - No Comments

HeadacheINTRODUCTION

Except perhaps for head colds, headaches are probably the most common human ailment. Three out of four Americans had a headache during the past year, according to the National Headache Foundation. Usually, headaches are merely passing annoyances that go away with aspirin or after a nap, but as many as 45 million US Citizens suffer from chronic and/or severe headaches that seriously interfere with their lives.

All told, headaches account for 80 million of all doctors’ office visits and more than 400 million dollars spent on over-the-counter pain relievers each year. Like colds, headaches are not completely understood by scientists. There appears to be various types of headaches, but any hard and fast classification is open to debate, in part, because the types often overlap - both in symptoms and in response to medication. Moreover, triggering factors and modes of relief vary from person to person. Still, the great majority of primary headaches (those not due to underlying diseases) fall into three categories, according to the International Headache Society: tension, migraine and cluster.

Tension Headaches
Similarly referred to as muscle-contraction or stress headache, tension headaches are the variety that everyone gets occasionally. The dull, steady pain - mild compared to migraine or cluster headaches - may be felt in the forehead, temples, back of neck or throughout the head. A feeling of tightness around the scalp is typical and muscles in the back of the upper neck may feel knotted and tender to the touch. It’s not known whether the sustained muscle-tension itself or the subsequent restricted blood flow causes the pain.

Tension headaches are associated with stress (often the pain comes after the stress has ended), fatigue or too much/too little sleep. Assuming a posture that tenses your neck and head muscles for long periods of time, such as holding your chin down whilst reading, can trigger these headaches; as can gum chewing, grinding your teeth or tensing head and neck muscles during sexual intercourse. Men and women are about equally likely to suffer tension headaches.

Tension headaches that occur daily may be a sign of clinical depression. In some cases, the headaches may cause the depression; in others, treating the depression makes the headaches go away.

Migraines
The word migraine, derived from the Greek, means “half a skull,” an apt introduction of the pain which usually occurs in only one side of the head. Migraines appear to involve the abnormal expansion and contraction of blood vessels in and around the brain. In some people, migraines start with distorted vision, called an “aura,” generally characterized by zigzag patterns of shooting lights, blind spots, and/or a temporary loss of peripheral vision. The throbbing, pulsating pain can be incapacitating and can last anywhere from a few minutes to several days. If longer, it’s probably not a migraine. Migraine sufferers may also experience nausea, vomiting and sensitivity to both light and noise.

About 80 percent of all migraine sufferers have a family history of the ailment and women are nearly four times more likely to be afflicted. The typical sufferer is young (under the age of 35) and had her first attack during her teens or twenties. With age, attacks usually become less severe and less frequent. Hormonal changes can play a role; thus susceptible women may have more attacks if they take oral contraceptives or around the time of menstruation. They may have fewer attacks during pregnancy and after menopause. Attacks can also be instigated by certain substances in food, emotional factors and environmental factors, such as glaring light, strong odours and changes in the weather.

Migraines are often accompanied by nausea and vomiting, and frequently affect only one side of the head. In the classic form, the pain follows certain warning signs (the aura), such as flashing lights, blind spots, tingling or numbness on one side of the body. The aura is always the same for each individual. An “abortive” migraine features the aura without the headache. Biofeedback and other non traditional techniques occasionally help prevent, though do not relieve, migraines; heat and other muscle-relaxing steps generally do not do either.

Since migraines may be sparked by specific factors, sufferers should keep a headache diary to pinpoint any possible triggers. People have blamed migraines on alcohol, monosodium glutamate (MSG), nitrites, and a host of other food and drinks. Birth control pills, oestrogen replacement therapy, menstruation, irregular eating, sleeping schedules, bright lights and noises have also been linked to migraines. The supposed migraine personality: compulsive, neat and rigid is probably a myth.

Cluster Headaches
These strike in a group or “cluster” for up to a few hours and recur daily for days, weeks or months on end. There may be months of freedom between attacks. Some researchers consider cluster headaches a variant of migraines, largely because the excruciating pain is centred on one side of the head, as in a migraine, but unlike the throbbing of a migraine, this pain is steady and piercing. There are other notable differences; typically cluster headaches strike at night or early morning and the pain is located around or behind one eye or in one temple.

Cluster headaches are about six to nine times more likely to strike men than women. The first attack usually appears in a person’s 20s or 30s. They are sometimes misdiagnosed as a sinus disorder (because stuffy nose or sinus congestion is a common symptom) or as an abscessed tooth. There’s no clear cause, though heavy smoking and drinking are possible contributing or triggering factors.

Treatment for Headache
Most headaches are tension headaches, caused by a muscle spasm in the back of the head and neck. The spasm can be sparked by emotional stress or by holding the head in a fixed position (for example, while facing a computer screen or driving for hours). Sometimes the pain can be very severe and felt in the back of the head and encircling the head in a vice-like band.

Tension headaches are sometimes helped by measures to relax the tight muscles. These include massage, hot showers and heating pads on the back of the neck or cold packs. Biofeedback and muscle-relaxation training may be helpful.

Some people find relief with other non-traditional techniques, such as acupuncture, hypnosis or meditation. Non-prescription pain relievers often help occasional tension headaches. If not, prescription analgesics may do the trick. These include Aspirin with Codeine (Empirin with Codeine); Acetaminophen with Codeine (Tylenol with Codeine); Aspirin, caffeine, and Butalbital (Fiorinal); or Aspirin and Oxycodone (Percodan).

For chronic tension headaches, prescription analgesics aren’t always useful. They tend to lose their effectiveness, encourage dependency, and cause “rebound” headaches when they wear off. A less addictive and often more effective alternative is a tricyclic antidepressant, such as Amitriptyline (Elavil) or Imipramine (Tofranil), which can affect the pain pathways in the brain. Tricylics must be used for several weeks before they take effect. Since much lower doses of the antidepressant are needed for pain than for depression, there are generally few or no side effects.

Drugs that constrict blood vessels, notably ergotamine (Ergostat), may relieve migraines if taken at the first sign of the headache. Once a migraine is established, the only recourse is to take a narcotic, such as Meperedine (Demoral) or Codeine, head for a darkened room and try to sleep it off. Recent studies show that no steroidal anti-inflammatory agents, such as Ibuprofen (Motrin), Indomethacin (Indameth), and others can alleviate migraines, sometimes as effectively as Ergotamine. A new drug, Sumatriptan (Imitrex), appears to ease migraines about as well as Ergotamine, with much milder side effects.

Preventing migraines requires different drugs than those used for relieving them. While neither Aspirin nor Acetaminophen will relieve migraines, recent research suggests that a regular aspirin regimen may help prevent them. Beta blockers taken daily are often effective, provided side effects (such as lowered pulse or blood pressure) do not develop. If you have asthma, don’t take beta blockers. Propranolol (Inderal) is the only beta blocker approved for migraines, but others may also help forestall attacks.

Cluster headaches seldom last more than an hour or two, but those hours - usually in the middle of the night - can be miserable. The attacks can occur daily, for weeks at a time, and then disappear for long stretches. These headaches don’t usually last long enough to be treated effectively. Some sufferers need prescription narcotics.

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[Sources: NIH, NHS direct]
[Compiled 12.09.08]

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Posted on: December 17, 2008

Filed under: General

Anxiety

4th December, 2008 - Posted by Andy - No Comments

Introduction
Fear and stress reactions are essential for human survival. They enable people to pursue important goals and to respond appropriately to danger. In a healthy individual, the stress response (fight, fright, or flight) is provoked by a genuine threat or challenge and is used as a spur for appropriate action.

An anxiety disorder, however, involves an excessive or inappropriate state of arousal characterized by feelings of apprehension, uncertainty, or fear. The word is derived from the Latin, angere, which means to choke or strangle. The anxiety response is often not attributable to a real threat. Nevertheless it can still paralyze the individual into inaction or withdrawal. An anxiety disorder persists, while a healthy response to a threat resolves, once the threat is removed.

Anxiety disorders have been classified according to the severity and duration of their symptoms and specific behavioural characteristics. Categories include:

• Generalized anxiety disorder (GAD), which is long lasting and low-grade
• Panic disorder, which has more dramatic symptoms
• Phobias
• Obsessive-compulsive disorder (OCD)
• Post-traumatic stress disorder (PTSD)
• Separation anxiety disorder (which is almost always seen in children)

GAD and panic disorder are the most common. Anxiety disorders are usually caused by a combination of psychological, physical, and genetic factors, and treatment is, in general, very effective.

Generalized Anxiety Disorder
Generalized anxiety disorder (GAD) is the most common anxiety disorder. It affects about 5% of UK citizens over the course of their lifetimes. It is characterized by the following:

A more-or-less constant state of worry and anxiety, which is out of proportion to the level of actual stress or threat in their lives. This state occurs on most days for more than 6 months despite the lack of an obvious or specific stressor. (It worsens with stress, however.)
It is very difficult to control worry. For a clear diagnosis of GAD, the specific worries should be differentiated from those that would define other anxiety disorders, such as fear of panic attacks or appearing in public. Moreover, they are not obsessive like those with obsessive-compulsive disorder. (It should be noted, however, that over half of those with GAD also have another anxiety disorder or depression.) Patients with anxiety may experience physical symptoms (such as gastrointestinal complaints) in addition to, or even in place of, mental worries. (This latter case may be more common in people from non-Western cultures such as those with Asian backgrounds.) People with GAD tend to be unsure of themselves, overly perfectionist, and conforming.

Given these conditions, a diagnosis of GAD is confirmed if three or more of the following symptoms are present (only one for children) on most days for 6 months:

• Being on edge or very restless
• Feeling tired
• Having difficulty with concentration
• Being irritable
• Having muscle tension
• Experiencing disturbed sleep

Symptoms should cause significant distress and impair normal functioning and not be due to a medical condition, another mood disorder, or psychosis. It should be noted that pure GAD is uncommon. It typically occurs with other mood disorders (anxiety or depression) or substance use. In one 8-year study, nearly three-quarters of GAD patients experienced depression at some point during the course of the study. A third of GAD patients had at least two other disorders of mood, substance use, or both.

Panic Disorder
Panic disorder is characterized by periodic attacks of anxiety or terror (panic attacks). They usually last 15 - 30 minutes, although residual effects can persist much longer. The frequency and severity of acute states of anxiety determine the diagnosis. (It should be noted that panic attacks can occur in nearly every anxiety disorder, not just panic disorder. In other anxiety disorders, however, there is always a cue or specific trigger for the attack.) A diagnosis of panic disorder is made under the following conditions:

A person experiences at least two recurrent, unexpected panic attacks, and for at least a month following the attacks, the person fears that another will occur.

Symptoms of a Panic Attack. During a panic attack a person feels intense fear or discomfort with at least four or more of the following symptoms: Rapid heart beat; Sweating; Shakiness; Shortness of breath; A choking feeling or a feeling of being smothered; Dizziness; Nausea; Feelings of unreality; Numbness; Either hot flashes or chills; Chest pain; A fear of dying; A fear of going insane

Women may be more likely than men to experience shortness of breath, nausea, and feelings of being smothered. More men than women have sweating and abdominal pain. Panic attacks that include only one or two symptoms, such as dizziness and heart pounding, are known as limited-symptom attacks. These may be either residual symptoms after a major panic attack or precursors to full-blown attacks. (It should be noted that panic attacks can also accompany other anxiety disorders, such as phobias and post-traumatic stress disorder. In such cases, however, additional characteristics differentiate these disorders from panic disorder.)

Frequency of Panic Attacks. Frequency of attacks can vary widely. Some people have frequent attacks (for example, every week) that occur for months; others may have clusters of daily attacks followed by weeks or months of remission.

Triggers of Panic Attacks. Panic attacks may occur spontaneously or in response to a particular situation. Recalling or re-experiencing even harmless circumstances surrounding an original attack may trigger subsequent panic attacks.

Phobic Disorders
Phobias, manifested by overwhelming and irrational fears, are common. In most cases, people can avoid or at least endure phobic situations, but in some cases, as with agoraphobia, the anxiety associated with the feared object or situation can be incapacitating.

Agoraphobia Agoraphobia has been somewhat misleadingly described as fear of open spaces, the term having been derived from the Greek word agora, meaning outdoor marketplace. In its severest form, agoraphobia is characterized by a paralyzing terror of being in places or situations from which the patient feels there is neither escape nor accessible help in case of an attack. (One patient described the terror of going outside as opening a door onto a landscape filled with snakes.) Consequently, people with agoraphobia confine themselves to places in which they feel safe, usually at home. The patient with agoraphobia often makes complicated plans in order to avoid confronting feared situations and places.

Social Phobia Social phobia, also known as social anxiety disorder, is the fear of being publicly scrutinized and humiliated and is manifested by extreme shyness and discomfort in social settings. This phobia often leads people to avoid social situations and is not due to a physical or mental problem (such as stuttering, acne, or personality disorders). The incidence of social phobia is approximately 13% and has been termed “the neglected anxiety disorder” because it is often missed as a diagnosis. The associated symptoms vary in intensity, ranging from mild and tolerable anxiety to a full-blown panic attack. (Unlike a panic attack, however, social phobia is always directly related to a social situation.) Symptoms include sweating, shortness of breath, pounding heart, dry mouth, and tremor. The disorder may be further categorized as generalized or specific social phobia:

Generalized social phobia is the fear of being humiliated in front of other people during nearly all social situations. People with this subtype are the most socially impaired and also the most likely to seek treatment.

Specific social phobia usually involves a phobic response to a specific event. Performance anxiety (”stage fright”) is the most common specific social phobia and occurs when a person must perform in public. These patients usually feel comfortable in informal social situations.

Children with social anxiety develop symptoms in settings that include their peers, not just adults, and they may include tantrums, blushing, or not being able to speak to unfamiliar people. These children should be able to have normal social relationships with familiar people, however.

Specific Phobias. Specific phobias (formerly simple phobias) are an irrational fear of specific objects or situations. Specific phobias are among the most common medical disorders. Most cases are mild and not significant enough to require treatment.

The most common phobias are fear of animals (usually spiders, snakes, or mice), flying (pterygophobia), heights (acrophobia), water, injections, public transportation, confined spaces (claustrophobia), dentists (odontiatophobia), storms, tunnels, and bridges. When confronting the object or situation, the phobic person experiences panicky feelings, sweating, avoidance behaviour, difficulty breathing, and a rapid heartbeat. Most phobic adults are aware of the irrationality of their fear, and many endure intense anxiety rather than disclose their disorder.

Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) has been described as hiccups of the mind. OCD is time-consuming, distressing, and can disrupt normal functioning. Much research suggests that a critical feature in this disorder is an over-inflated sense of responsibility, in which the patient’s thoughts centre around possible dangers and an urgent need to do something about it.

Obsessions are recurrent or persistent mental images, thoughts, or ideas. The obsessive thoughts or images can range from mundane worries about whether one has locked a door to bizarre and frightening fantasies of behaving violently toward a loved one.

Compulsive behaviours are repetitive, rigid, and self-prescribed routines that are intended to prevent the manifestation of an associated obsession. Such compulsive acts might include repetitive checking for locked doors or unlit stove burners or calls to loved ones at frequent intervals to be sure they are safe. Some people are compelled to wash their hands every few minutes or to spend inordinate amounts of time cleaning their surroundings in order to subdue the fear of contagion.

Over half of OCD-sufferers have obsessive thoughts without the ritualistic compulsive behaviour. Although individuals recognize that the obsessive thoughts and ritualized behaviour patterns are senseless and excessive, they cannot stop them in spite of strenuous efforts to ignore or suppress the thoughts or actions. OCD often accompanies depression or other anxiety disorders. There is some evidence that the symptoms improve over time and that nearly half will eventually recover completely or have only minor symptoms.

Symptoms in children may be mistaken for behavioural problems (taking too long to do homework because of perfectionism, refusing to perform a chore because of fear of germs). Children do not usually recognize that their obsessions or compulsions are excessive.

Associated Obsessive Disorders Certain other disorders that may be part of, or strongly associated with, the OCD spectrum include the following:
Body Dysmorphic Disorder (BDD). In BDD, people are obsessed with the belief that they are ugly, or part of their body is abnormally shaped.

Trichotillomania People with trichotillomania continually pull their hair, leaving bald patches.

Tourette Syndrome Symptoms of Tourette syndrome include jerky movements, tics, and uncontrollably uttering obscene words.
Obsessive-Compulsive Personality. OCD should not be confused with obsessive-compulsive personality, which defines certain character traits (e.g., being a perfectionist, excessively conscientious, morally rigid, or preoccupied with rules and order). These traits do not necessarily occur in people with obsessive-compulsive disorder.

Post-Traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a severe, persistent emotional reaction to a traumatic event that severely impairs one’s life. It is classified as an anxiety disorder because of its symptoms. Not every traumatic event leads to PTSD, however. There are two criteria that must be present to qualify for a diagnosis of PTSD:

The patient must have directly experienced, witnessed, or learned of a life-threatening or seriously injurious event.
The patients’ response is intense fear, helplessness, or horror.

Children may behave with agitation or with disorganized behavior.

Triggering Events. PTSD is triggered by violent or traumatic events that are usually outside the normal range of human experience. There is some evidence that events most likely to trigger PTSD are those that involve deliberate and destructive behavior (e.g., murder, rape) and those that are prolonged or physically challenging. The event can also be a natural disaster. Such events include, but are not limited to, experiencing or witnessing sexual assaults, accidents, combat, natural disasters (such as earthquakes), or unexpected deaths of loved ones. PTSD may also occur in people who have serious illness and receive aggressive treatments or who have close family members or friends with such conditions.

Symptoms of PTSD. There are three basic sets of symptoms associated with PTSD. They may begin immediately after the event or can develop up to a year afterward:
Re-experiencing. In such cases, patients persistently re-experience the trauma in at least one of the following ways: in recurrent images, thoughts, flashbacks, dreams, or feelings of distress at situations that remind them of the traumatic event. Children may engage in play, in which traumatic events are enacted repeatedly.

Avoidance. Patients may avoid reminders of the event, such as thoughts, people, or any other factors that trigger recollection. They tend to have an emotional numbness, a sense of being in a daze or of losing contact with their own identity or even external reality. They may be unable to remember important aspects of the event.
Increased Arousal. This includes symptoms of anxiety or heightened awareness of danger (sleeplessness, irritability, being easily startled, or becoming overly vigilant to unknown dangers).

To further qualify for a diagnosis of PTSD, patients must have at least one symptom in the re-experiencing category, three avoidance symptoms, and two arousal symptoms. Symptoms are chronic (3 months or more). Symptoms should also not be associated with alcohol, medications, or drugs and should not be intensifications of a pre-existing psychological disorder.

Acute Stress Disorder. Experts have identified a syndrome called acute stress disorder, in which symptoms of PTSD occur within 2 days to 4 weeks after the traumatic event. Acute stress disorder can accurately identify up to 94% of victims at risk for PTSD. Between 50 - 80% of these patients actually develop the more chronic and serious disorder. In other words, it is very sensitive for identification of those at highest danger for PTSD but less successful in determining specifically who will or will not recover emotionally.

Long-Term Outlook. The long-term impact of a traumatic event is uncertain. In one study of people who survived a mass killing spree in Texas, less than half of those who suffered PTSD (28% of all survivors) had recovered after a year. In another study, PTSD became chronic in 46% of the subjects. In fact, PTSD may cause physical changes in the brain, and in some cases the disorder can last a lifetime.

Separation Anxiety Disorder
Separation anxiety disorder almost always occurs in children. It is suspected in children who are excessively anxious about separation from important family members or from home. For a diagnosis of separation anxiety disorder, the child should also exhibit at least three of the following symptoms for at least 4 weeks:

Extreme distress from either anticipating or actually being away from home or being separated from a parent or other loved one
Extreme worry about losing or about possible harm befalling a loved one
Intense worry about getting lost, being kidnapped, or otherwise separated from loved ones
Frequent refusal to go to school or to sleep away from home
Physical symptoms such as headache, stomach ache, or even vomiting, when faced with separation from loved ones

Separation anxiety often disappears as the child grows older, but if not addressed, it may lead to panic disorder, agoraphobia, or combinations of anxiety disorders.

[Sources: NIH, NHS Direct]

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Posted on: December 4, 2008

Filed under: General